What condition is Ospemifene primarily used to treat?

Ospemifene is primarily used to treat moderate to severe dyspareunia, which is painful intercourse often associated with vaginal dryness, commonly seen in postmenopausal women. Ospemifene is a selective estrogen receptor modulator (SERM) that acts on estrogen receptors in certain tissues, particularly in the vaginal and vulvar areas, to alleviate symptoms of vaginal atrophy and improve the quality of vaginal tissue.

This therapeutic action helps to restore vaginal moisture and elasticity, thereby reducing pelvic discomfort during sexual activity, making it an effective treatment option for women experiencing this condition. Its mechanism of action offers a non-hormonal approach to improving sexual health in women who may not be able to or prefer not to use traditional hormone replacement therapies.