What is a common physical finding associated with Vitamin B12-deficiency anemia?

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Vitamin B12-deficiency anemia can manifest through a variety of physical findings, all of which assist in diagnosing the condition. A common physical finding includes a smooth, beefy-red tongue, which occurs due to the loss of papillae on the tongue's surface. This change is a direct result of the deficiency impacting the mucosal health.

Additionally, the skin may appear pale, and in some cases, this can be accompanied by jaundice. Jaundice is typically the result of increased hemolysis due to the anemia's effects, leading to elevated bilirubin levels.

Cardiovascular effects can also be present, such as tachycardia and arrhythmias. These symptoms arise as the heart tries to compensate for reduced oxygen-carrying capacity due to anemia.

Thus, the correct answer encapsulates the spectrum of physical findings associated with Vitamin B12 deficiency, highlighting the multifaceted nature of this anemia. The variety of symptoms—ranging from changes in the oral cavity to systemic effects—demonstrate the wide-ranging impact that Vitamin B12 deficiency can have on the body.

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