What is the primary use of Bazedoxifene?

Bazedoxifene is classified as a selective estrogen receptor modulator (SERM), which means it can have varying effects on different types of tissues in the body. Its primary use revolves around its role in the treatment of menopausal symptoms and prevention of osteoporosis in postmenopausal women. Bazedoxifene exhibits mixed effects; it can act as an estrogen agonist in some tissues while functioning as an antagonist in others, such as breast and endometrial tissues.

This dual action is crucial because it allows Bazedoxifene to provide benefits associated with estrogen (like bone preservation) without stimulating the endometrial lining or breast tissue in ways that would increase the risk of cancer. In contrast, its utility as a contraceptive is not relevant, as its modes of action do not include contraception. Hormone replacement therapy also encompasses a broader range of options that include estrogen, progesterone, and combinations thereof, typically not limited to SERMs. Lastly, Bazedoxifene is not used as an antidepressant; its mechanism of action does not pertain to mood stabilization or treatment of depression disorders. Thus, option C accurately captures the primary therapeutic role and unique properties of Bazedoxifene.