When prescribing an oral contraceptive containing drospirenone, which medication should be considered in the woman's health history?

When prescribing an oral contraceptive that contains drospirenone, it is important to pay particular attention to the patient's health history concerning medications that might increase the risk of hyperkalemia. Drospirenone is a synthetic progestin that has some anti-mineralocorticoid effects, which can lead to increased potassium levels in the body.

Among the listed medications, ACE inhibitors are known to contribute to elevated potassium levels. When used in conjunction with drospirenone, there is a significant risk that the combined effect could lead to hyperkalemia, posing a potential cardiovascular risk. Therefore, careful assessment of the woman’s history with ACE inhibitors is vital to ensure her safety while on this contraceptive.

By monitoring potassium levels and reviewing the patient's complete medication profile, a healthcare provider can mitigate risks associated with the use of drospirenone and maintain patient safety. It’s also beneficial to guide the patient on recognizing symptoms of hyperkalemia if they are on these medications concurrently.